论著摘要 |【CT】心脏计算机断层扫描影像组学技术的综述(双语版)

2017-09-21 17:37:52 admin 0

Cardiac Computed Tomography Radiomics: A Comprehensive Review on Radiomic Techniques.

发表日期: 2017.04.14   来源: J Thorac Imaging, 2017.

作者

Kolossváry, M.*, Kellermayer, M.#, Merkely, B.*, Maurovich-Horvat, P.*

作者介绍:

*MTA-SE Cardiovascular Imaging Research Group, Heartand Vascular Center;

#Department of Biophysics and Radia-tion Biology, Semmelweis University, Budapest, Hungary

 

摘要

影像组学图像是大量的三维数据集,其中基于体积的每个体素都代表独特的组织相关特征的物理测量。技术的进步使得放射科医师可以用不可预见的细节影像病理形态,从而进一步增加待处理的信息量。即使成像方式进步很大,我们对图像的解释几十年来基本没有变化。我们已经到了精准医疗的时代,可以看到疾病表现的微小差异,作为新的干预策略的潜在靶点。如果我们希望跟上其他诊断领域的进展,迫切需要改进和扩大对于影像组学图像的解释。影像组学是从给定的感兴趣区域提取大量数量特征以创建大数据集的过程,其中每个异常形态由数百个参数描述。从这些参数中挖掘数据,探索和建立变量与临床数据之间新的有意义的相关性。在结果的基础上建立预测模型,这可能会扩大我们对疾病的认识,并帮助临床决策。影像组学是一个复杂的学科,涉及不同学科的交叉;我们的目标是解释常用的影像组学技术,并回顾目前在心脏计算机断层扫描(CT)成像中的应用。

 

Abstract

Radiologic images are vast three-dimensional data sets in which each voxel of the underlying volume represents distinct physical measurements of a tissue-dependent characteristic. Advances in technology allow radiologists to image pathologies with unforeseen detail, thereby further increasing the amount of information to be processed. Even though the imaging modalities have advanced greatly, our interpretation of the images has remained essentially unchanged for decades. We have arrived in the era of precision medicine where even slight differences in disease manifestation are seen as potential target points for new intervention strategies. There is a pressing need to improve and expand the interpretation of radiologic images if we wish to keep up with the progress in other diagnostic areas. Radiomics is the process of extracting numerous quantitative features from a given region of interest to create large data sets in which each abnormality is described by hundreds of parameters. From these parameters datamining is used to explore and establish new, meaningful correlations between the variables and the clinical data. Predictive models can be built on the basis of the results, which may broaden our knowledge of diseases and assist clinical decision making. Radiomics is a complex subject that involves the interaction of different disciplines; our objective is to explain commonly used radiomic techniques and review current applications in cardiac computed tomography imaging.

 

 关键词:

放射组学,心血管疾病,心脏CT

KEYWORDS:

radiomics, cardiovascular disease, cardiac computedtomography

阅读原文:DOI: 10.1097/RTI.0000000000000268


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