论著摘要 |【综述】影像组学的兴起及其在肿瘤管理中的应用前景(双语版)

2017-10-09 11:37:40 admin 1

The Rise of Radiomics and Implications for Oncologic Management.

发表日期: 2017.07.01   来源:Journal of the National Cancer Institute, 2017, 109(7).

作者

Verma V1, Simone CB 2nd2, Krishnan S3, Lin SH3, Yang J3, Hahn SM3.

作者介绍: ,

1. Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, USA.

2. Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, MD, USA.

3. Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

摘要

临床医学,尤其是肿瘤学慢慢在向个性化医疗发展。在过去的几十年中,基因组学,蛋白组学,转录组学,代谢组学的研究在个性化医疗中占据着主要地位。然而,影像组学的概念在2012年才被提及。新生的影像组学对个性化癌症护理有重大影响,同时也涉及到了从CT/MR的诊断图像中提取到标准化可量化的图像特征。影像组学的主要假设是他将代表的是个性化,可量化的,基于多维参数的医疗诊断数据库,他将针对性的关联于不同的临床个体,而目前临床诊断仍然用传统的影像学,组织学等临床数据。影像组学在医疗诊断中蕴含着巨大潜力,但是在肿瘤病人的诊断中仍然并非主流。因此作者将在本文探讨影像组学在未来的癌症诊疗中的作用。

Abstract

Clinical medicine, particularly oncology, is progressing toward personalized care. Whereas the terms genomics, proteomics, transcriptomics, and metabolomics have dominated personalized medicine for the past couple decades, the concept of radiomics was first described in 2012. This nascent concept has major implications for personalized cancer care and involves extracting hundreds of standardized and quantifiable imaging characteristics from diagnostic computed tomography/magnetic resonance imaging images. The central hypothesis of radiomics is that these libraries of quantitative individual voxel-based variables are more sensitively associated with various clinical endpoints compared with the more qualitative radiologic, histopathologic, and clinical data more commonly utilized today. Because radiomics offers immense potential but has not reached a mainstream oncologic audience, the authors discuss herein the role of radiomics in cancer care in the future.

阅读原文:DOI: 10.1093/jnci/djx055

 

 


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