论著摘要 |【Radiomics-概述】基于人群的成像和放射学:德国国家队列MRI研究的理论和观点(双语版)

2018-01-23 12:57:28 admin 0
标签:   影像组学 MRI 全身磁共振成像 德国国家队列 概述

Population-Based Imaging and Radiomics: Rationale and Perspective of the German National Cohort MRI Study.

发表日期: 2016.05.03   来源:Rofo. 2016 Jul;188(7):652-61.

作者:

Schlett CL1, Hendel T2, Weckbach S1, Reiser M2 , Kauczor HU1, Nikolaou K3, Günther M4, Forsting M5, Hosten N6, Völzke H7, Bamberg F3.

作者介绍:

1. Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg.

2. Department of Clinical Radiology, Klinikum der Universität München, Campus Großhadern, München, Germany.

3. Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Germany.

4. MEVIS, Fraunhofer, Bremen, Germany.

5. Department of Diagnostic and Interventional Radiology and Neuroradiology, Univ. Duisburg-Essen, Medical Faculty, Essen, Germany.

6. Department of Diagnostic Radiology and Neuroradiology, Ernst-Moritz-Arndt-University, Greifswald, Germany.

7. Community Medicine, Universitätsklinikum Greifswald, Germany.

摘要

德国国家队列的MRI研究在德国进行了大规模的基于人群的纵向研究,包括使用3-Tesla全身MR成像的总共3万名参与者的综合表征和表型。与专门的核心设施建立了多中心的研究设计来管理偶然发现或提供质量保证。因此,该研究代表了一个独特的机会,大大影响基于成像的风险分层,导致个性化和精确的医学。 在计算科学领域的发展的支撑下,新兴的影像学领域对未来具有很大的潜力。 在本文中,我们提供了基于人群的成像和影像的概述,并概述了德国国家队列中MRI研究的理论和设计。

Abstact

The MRI study within the German National Cohort, a large-scale, population-based, longitudinal study in Germany, comprises comprehensive characterization and phenotyping of a total of 30 000 participants using 3-Tesla whole-body MR imaging. A multi-centric study design was established together with dedicated core facilities for e. g. managing incidental findings or providing quality assurance. As such, the study represents a unique opportunity to substantially impact imaging-based risk stratification leading to personalized and precision medicine. Supported by the developments in the field of computational science, the newly developing scientific field of radiomics has large potential for the future. In the present article we provide an overview on population-based imaging and Radiomics and conceptualize the rationale and design of the MRI study within the German National Cohort.

关键词:

德国国家队列;基于人群的影像;纵向队列研究;全身磁共振成像;表现型;影像组学

Keywords:

German National Cohort; population-based imaging; longitudinal cohort study; whole-body magnetic resonance imaging; phenotyping; radiomics

阅读原文:PMID: 27139177  DOI: 10.1055/s-0042-104510


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